ABSTRACT
Objective:To investigate the medium- and long-term efficacy of peroral endoscopic myotomy (POEM) for esophageal diverticulum and the risk factors for postoperative recurrence.Methods:A retrospective study was conducted on 31 cases of esophageal diverticulum who were treated by POEM in Zhongda Hospital, Southeast University from May 1st 2016 to August 1st 2019. The Eckardt score, the operative success rate, and the recurrence rate after the operation were observed and recorded. Multivariate logistic regression analysis was performed to explore the risk factors for postoperative recurrence.Results:POEM was successfully completed in all 31 patients, who were followed up for 30.6±11.1 months (20-63 months). The Eckardt score before the operation was 8.2±2.4, and was 1.4±0.7, 1.4±1.1, 1.3±1.1, and 1.3±0.9 at 1, 6, 12 and 24 months, respectively after the operation, which significantly decreased at all follow-up time points ( P<0.001). The success rates at 1, 6, 12, and 24 months after the operation were 96.8% (30/31), 90.3% (28/31), 90.3% (28/31) and 90.3% (28/31), respectively. Three patients suffered symptom relapse, with an overall recurrence rate of 9.7% (3/31). Logistic regression analysis showed that the disease duration ( P=0.038, OR=1.041, 95% CI: 1.002-1.080) and preoperative Eckardt score ( P=0.024, OR=2.299, 95% CI: 1.117-4.728) were risk factors for postoperative recurrence of POEM. Conclusion:POEM is safe and effective for esophageal diverticulum. Patients with long disease duration and high preoperative Eckardt score are associated with recurrence.
ABSTRACT
To investigate the effectiveness and safety of diverticular peroral endoscopic myotomy (D-POEM) for mid-esophageal diverticulum. Data of consecutive patients in the prospective database with mid-esophageal diverticulum who received D-POEM in West China Hospital, Sichuan University between April 2014 to September 2019 were collected. The modified Eckardt scoring system for mid-esophageal diverticulum was used to evaluate the severity of diverticular symptoms. The effectiveness and safety of D-POEM were evaluated in terms of clinical success, technical success, complications and recurrence. A total of 7 patients with mid-esophageal diverticulum were included. Clinical and technical success was achieved in all patients with operation time of 16-70 minutes. No serious complications (2 cases with minor complications) or recurrence occurred. The follow-up time was 2-16 months. The median modified Eckardt score decreased from 3 points before operation to 0 points after operation. It is preliminarily believed that D-POEM ensures a complete septotomy between normal esophageal lumen and esophageal diverticulum. It is a safe and effective technique for mid-esophageal diverticulum. The modified Eckardt scoring system is suitable for symptom evaluation before and after treatment of mid-esophageal diverticulum.
ABSTRACT
Introdução:Divertículos esofagianos são alterações esofá-gicas raras e podem ser classificados em proximais, médios ou distais, de acordo com a localização. Podem ser de pulsão ou tração e verdadeiro ou falso. Na dependência do tamanho do divertículo e da concomitância de doença associada, po-dem causar disfagia, regurgitação, mau hálito, rouquidão ou pneumopatias, podendo ter indicação de ressecção cirúrgica. O diagnóstico é suspeitado pela história clínica e confirmado pelo exame radiológico contrastado e pela endoscopia diges-tiva alta. Objetivo: Relatar o caso raro de uma paciente com divertículo de esôfago médio. Materiais e Métodos: Revisão do prontuário, registro fotográfico dos métodos diagnósticos e revisão da literatura. Resultados: Paciente feminina, 61 anos, encaminhada ao ambulatório do hospital de base de São José do Rio Preto, com queixa de disfagia progressiva para alimentos sólidos aproximadamente há cinco anos, associado à odinofagia, eructação intensa e perda ponderal nesse período de 10 quilos. A endoscopia digestiva alta, mostrou divertículo no terço médio do esôfago, 25 cm da arcada dentária supe-rior, com óstio de 3-4 cm de diâmetro e 3 cm de profundidade. A tomografia computadorizada de tórax confirmou a presen-ça do divertículo de esôfago em terço médio do esôfago, sem outros achados que justificassem sua presença. A paciente foi submetida à videotoracoscopia com ressecção do divertículo sem intercorrências. Atualmente, a paciente apresenta-se as-sintomática no acompanhamento clínico. Conclusão: Embora seja considerada uma alteração esofágica rara, os divertículos esofagianos, devem sempre ser considerados como diagnósti-co diferencial. Especialmente em casos de disfagia, halitose e enfermidades respiratórias por broncoaspiração. Em casos de pacientes sintomáticos e com dificuldade no tratamento clinico, a melhor opção terapêutica é a cirurgia com a excisão local do divertículo via toracotomia ou toracoscopia.
Introduction:Esophageal diverticula are rare conditions of the esophagus and can be classified according to their location in proximal, middle, or distal. Further categorization relates to presumed etiology, namely traction vs pulsion, true or false. Depending on the size of the diverticulum and the concomitance of associated disease, it can cause dysphagia, regurgitation, bad breath, hoarseness or pneumopathies. Thus, symptomatic patients are eligible surgical resection. The diagnosis is suspected by clinical history and confirmed by contrast radiological examination and upper digestive endoscopy. Objective: Present the case of a patient with middle esophageal diverticulum. Materials and Methods: We carried out a review of medical records, photographic record of diagnostic methods, and review from the literature. Results: A 61-year-old female patient was referred to the outpatient clinic at a teaching hospital (Hospital de Base), located in the city the São José do Rio Preto, inland of São Paulo State due to progressive complaints of dysphagia for solid foods for about 5 years, associated with odynophagia and severe eructation. She had a 10 kg weight loss in this period. Upper digestive endoscopy showed a diverticulum in the middle third of the esophagus, 25 cm from the dental arcade, with an ostium diameter of 3-4 cm and depth of 3 cm. A chest computed tomography confirmed the presence of an esophageal diverticulum in the middle third of the esophagus, in addition to other findings that justify its presence. She underwent video-assisted thoracoscopy with diverticulum resection without further complications. Currently, she is asymptomatic in clinical follow-up. Conclusion: Although it is considered a rare outgrowth, esophageal diverticula should always be considered as a differential diagnosis, especially in cases of dysphagia, halitosis, and respiratory diseases due to bronchoaspiration. In cases of symptomatic patients with difficulty to undergo clinical treatment, the best therapeutic option is a surgery with local excision of the diverticulum via thoracotomy or thoracoscopy.
Subject(s)
Humans , Female , Middle Aged , Deglutition Disorders/diagnostic imaging , Diverticulosis, Esophageal/diagnostic imaging , Esophageal Diseases/diagnostic imagingABSTRACT
ABSTRACT Epiphrenic diverticulum is a rare disease associated with esophageal motor disorders that is usually asymptomatic and has a well-established surgical indication. We report a case of giant epiphrenic diverticulum in a 59-year-old symptomatic woman who was diagnosed after underwent complementary exams. Because of her symptoms, the surgical treatment was chosen, and esophageal diverticulectomy was performed along with laparoscopic cardiomyotomy and anterior partial fundoplication.
RESUMO O divertículo epifrênico é uma patologia rara associada a distúrbios motores esofágicos e, frequentemente, assintomática, tendo indicações cirúrgicas bem estabelecidas. Relatamos um caso de divertículo epifrênico gigante em paciente de 59 anos, sexo feminino, sintomática, diagnosticada por exames complementares. Devido à sintomatologia, optou-se por tratamento cirúrgico, sendo realizada a diverticulectomia esofágica com cardiomiotomia e fundoplicatura parcial anterior laparoscópica.
Subject(s)
Humans , Female , Middle Aged , Postoperative Complications/etiology , Diverticulum, Esophageal/surgery , Laparoscopy/methods , Fundoplication/methodsABSTRACT
O divertículo de Zenker é um pseudodivertículo que se origina de um defeito muscular na parede posterior da faringe, na área de transição entre o músculo constritor inferior da faringe e o músculo cricofaringeo. Apesar do avanço das técnicas endoscópicas, o tratamento cirúrgico persiste como o tratamento padrão. Duas técnicas são possíveis: diverticulectomia (ressecção do divertículo) e a diverticulopexia. As vantagens da diverticulopexia estão ligadas à ausência de anastomose esofágica e suas possíveis complicações: fistulas cervicais, mediastinite, estenose esofágica e infecção de ferida. Em ambas as técnicas a secção das fibras musculares do músculo cricofaringeo (ou, esfíncter superior do esôfago) é fundamental. O objetivo do presente artigo é descrever em detalhes a técnica de diverticulopexia junto ao ligamento pré-vertebral associada à miotomia do músculo cricofaríngeo.
Zenker´s diverticulum is a pseudodiverticulum through a muscular defect in the posterior pharyngeal wall at the area between the inferior pharyngeal constrictor muscles of the pharynx and the cricopharyngeus muscle. Although endoscopic techniques have made significant progress, the surgical treatment remains the gold standard. There are two main techniques: diverticulectomy (resection of the diverticulum) and diverticulopexy. The main advantages of diverticulopexy are mostly linked to the absence of an esophageal anatomosis and its possible complications: cervical fistulae, mediastinitis, esophageal stenosis and wound infection, which allows a rapid recover with satisfactory oral intake. The purpose of this article is to describe in details the technique for diverticulopexy to the prevertebral ligament in association with a miotomy of the cricopharyngeus muscle.
Subject(s)
Humans , Zenker Diverticulum/surgery , Digestive System Surgical Procedures/methodsABSTRACT
A 68-yr-old man complaining of sudden, postprandial chest pain visited the emergency room. His symptom had been aggravated during the preceding two days. Upper gastrointestinal contrast study with gastrographin showed leakage of dye from the epiphrenic diverticulum in the lower third of the esophagus. The primary repair was urgently carried out. Upper gastrointestinal contrast study 14 days after operation revealed an esophageal leakage which was small and confined. The patient was managed with conservative treatments such as intravenous hyperali-mentation and broad-spectrum antibiotics. Forty-two days after the operation, a gastrographin swallow study showed the absence of leaks. This is the first report-ed case of a perforated epiphrenic esophageal diverticulum repaired by delayed primary repair in Korea.
Subject(s)
Aged , Humans , Male , Diverticulum, Esophageal/complications , Esophageal Perforation/diagnosis , Esophagectomy/methods , Time Factors , Treatment OutcomeABSTRACT
Objective Our purpose was to improve the konwlege and diagnosis level of esophageal intramural pseudodiverticulosis(EIPD).Methods All 3 cases were underwent single and double contrast esophagograms.Analyze the findings on esophagography in 3 cases.Results Multiple small tiny cyst like outpouchings with a narrow neck extending outward esophageal wall were found in all of the 3 cases, the length range of outpouchings diameter was 1-4 mm,and the length range of neck was 1-2 mm,the pseudodiverticula had a diffuse distribution in 2 cases,and segmental distribution on the middle and the lower esophagus in the other case.Some necks of pseudodiverticula incline to stomach with 30?-45? in 2 cases;and intramural tracking was found in 1 case,the length range of tracking was 5-10 mm;esophageal stenosis in esophagogastic junction and reflux esophagitis was found only in 1 case;1 case underwent endoscopy and ostiums of pseudodiverticula were found;biopsy showed submucosal chronic inflammation surrounding the neck of pseudodiverticula,squamous metaplasia of the epithelium in both the neck and outpouchings.Conclusion EIPD is a rare benign disorder characterized by dilation of the submucosal glands.The value of esophagography is to distinguish sublimes ulcer caused by esophagitis and esophageal fenestrate from EIPD.The characteristic radiographic appearance is numerous intramural esophageal contrast-filled cystiform outpouchings,and some necks incline in the direction of stomach.When the typical appearance found on barium studies,the diagnosis of EIPD can be made.